SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2efbccdd553307a2b6a7005d4c51aae8f60bd4e0628a443c251c87544f1ef5f' 
  AND token = '1vYUnIAHbvaOvDXhOyA4IgUWBkL5OKVEMnKwtdTp+Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}