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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29313c4ecb5a4b7c0f213047a89398be324deea5fcf455a43c753ca0541d47d4' 
  AND token = 'XDwfso9ZKlhJxWW+FyUnH5BVaK1UU6iLs9MLe2HywX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}