SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fab7c5ac1b7cac97547194dfe52e1a9f8439c5d2c1abd0f12e441fbf5a9f357' 
  AND token = '3j7YB/SDNXPdjfiRAYkYf8bSld/eCOWZWjQrw85qbSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}