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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3922beb3cd555293134b130a5af54861144badbf41d77e3dc48e6d7035a4a1fc' 
  AND token = 'p91qiYEVe9Sxz1tFyqvBDQUyGJtbMesAei4+XT2gs18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}