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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f15208d7f22eb4f5c8b97be46e50a5b7e07a464f792a807ab6e4c7ba00c16bce' 
  AND token = 'wYGW6SQ1DPfZ2wDWDuEMdRASQYhG7YczFtqRjEumzpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}