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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1903db48fe8441e4ae7d9afd8f63218c440d380056f58df378cff81cf701379' 
  AND token = '52RIQA/Mh9ouJg95qOKKvq/pHlYtcSTvrNQ8Jva5aIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}