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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac42c2399424c57d1eedbd18edeb5616602ec653292529224853922574ccb7a5' 
  AND token = 'zSZtQ1ta1npWd9c6xWVvKM1GCAZn9fdi1rYROKh+6Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}