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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb5d998ccf6b98e708206d01c1e18f29508f8f576cee73f81e8f4f1c6fb96a68' 
  AND token = 'AguWfEBKE+QzS2ur1IsscMkM6/kGM3mPjwqXZ5e7Mlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}