SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7050f2f3929126cb3cdda2790db2acc004321c34acfc59995ac7f190b9e5bf6' 
  AND token = 'Fh6EdUMUdz6oSG+5SAPWpARG8v008VsL+ICBv5T8Ne0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}