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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4188df1f1954a5b1b0075b3d59de4ef5e5cafb221da124c8e744999b8816703' 
  AND token = 'ZkEnKn1zeWjnkixobvg8FMskLK9DzD7ekwannLerBn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}