SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00cdb46f3b7483e56f57e10e5946b31662721ca54d29d9e5b8ad4a37286b1c33' 
  AND token = 'I0YiUJuGGGs030oYKOouR1RKAEQN8TDeL3ophCe0+eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}