SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a8adfedd03a6245bc774dc38de435befe4ad36d3a9cd6ecdb9a175547e93198' 
  AND token = '1kjvGFAN9BcEhKVOmqAse3EdHod9iSxxrujf5ShO+YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}