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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cebe6f3faa0abf18d476857f2cdd0dc6a9d7e092b880423e7a4d536dc4a0f114' 
  AND token = '4VX6UMBVg1hB0c+6hflTqjnFfJ+WWvj4fmbPJsfbXhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}