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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c6267b4ff45291c4dbf79190b8c06061fae60bcfecd724d6976de01611c630' 
  AND token = '44z7OXHNwOXM+Uj5bSCBL4UBI7eN6QK/Vv+uED9KQIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}