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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbebbb45d536e9e4c04fa48cc55c6e331986590ba41c472a0fb2b536d18b77ac' 
  AND token = 'UyRw1JQ9kPVDIS09CZ4l6jsUxctz7zOcUrxL0Neds0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}