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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a26b6af6f15e7d182945e8f391709bb94c50798e05564f3af3de9acd0070d588' 
  AND token = 'CKhAZrmy4QuAc25HRY+tDL1/T28DS363bPOsUNQkohQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}