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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdb3a1849be1b0dad9aaf4f1d0482231e3709375f3aefc2b656f45d031d943e7' 
  AND token = 'PtJgr9mFFeOMCoH15gEmKO7Io+RMnaDT/ULz7jasRIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}