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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64faf4a2f8328c880a9a63ceb21bdf08bde29646782bcc039554552163d3f474' 
  AND token = 'UcHvhrexQWEmQCbwELhbDtCM4whUHq/6IAX1Uj4w4os=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}