SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea474752d7bd97746133774cd7abfb20c88b850916737d439fce90beb5c3a536' 
  AND token = '5O3N+iJVeZeznO+I9ECG1fzujSxqLb6TzWGEZU+6TFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}