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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9fe225a192a4de5454e0fbf8bf5801335bd842afbef9d5c2f35aedfe09d8fee' 
  AND token = 'bOM4uD4gA8CPrM8sNnsDbZWNUmXDprP7HDeC8OVWnn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}