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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd900ccc0f2e0338e8d6caf9cf977c134d649b3d245eb0d65e6178fcdcec92781' 
  AND token = '5xGX7+9mfuojs7h/0xH3kWXhl6pNdocl3SC0GWXkf1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}