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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad04caeda1e00257afaaea1e731a50c6b10c14272becfa140caf9111cdb4a24' 
  AND token = 'LgJV2D03zNzY2+8q6Oyhp3uUQ3hJAfqg61/BBgw+E7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}