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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18dfd4c1f70d2ccd4200a7d3a517a49b220e4f141b7aad8f854acd351aa8fa50' 
  AND token = 'RH7Vw8WOKoh/KXSBy99KCQ6DVwiio6FJxF6wGNSKQxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}