SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e053d21c6026bfc3464fc0a8ace5d323b732f0a550d28baa8a8e1b6cb3c2b94' 
  AND token = '7m0VhcxMZEGAxpMxyFyDeLhw8UEUFxPV4ByD6dFDYvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}