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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '080ecf56bd47a38f4b15f2cb23fc7bf544307f0ee7a48d0c8306da44a52475f6' 
  AND token = 'Rxsk4g1r/Z6rQcfM3A9ZX9slPTpmyrbhChUXgkgiGRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}