SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743beadf6c474f931d5af0a85d97afc7c32627bc3969ed032a491f8ebdffe07c' 
  AND token = 'TzmwVZrQ5mgw7aXZH4IYG1lmDH9m9/+MLUVNaq2tnzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}