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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b598f4475a9567358c48e5f89f40c1a7ea144c72488b1b5767c73b839604b5a6' 
  AND token = '+x9OG0r2HKZMTYrcOLcLRB86N8FZGbuAKEpKKZpIGwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}