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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653f748744a55976614d7a04dd53e4f245bb3b4c9c40fd7b25023da574912623' 
  AND token = 'VqH2nxwCGXSf8jHtOhh9H0s90ktEKcX49ubIUqrS/3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}