SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10fe00f37f57a00a10edec458f424f2d7762aea016faa390fa40f1dfe8658279' 
  AND token = '6Ki9Yx38dD0kzi0VQgNv+InRIw229XKVzh0uqRH+WcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}