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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99f194d759f5cd269cc41dcde6f8e990986a887c940d7a90b65d273f6a2f8a86' 
  AND token = 'sFpj7Rcd06X5rBkP7DjJGuzMsZ+Tcia5cB9LZs2BdyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}