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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21595e5b9c6ed56b54c15be9a4e7962f332323bcc7a848f7df4f4599648efce8' 
  AND token = 'kwJyDRcHEOoP3xxr7wbiTbcTITCiS6kmec6lUk72k+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}