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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e6eea063a603a2fb2f4ff117991b658d7cc6064a4122de2f3f159370438ce2' 
  AND token = 'B8OsXbhZ4+4mgpMpCzaeBVl6VlWe+/il1gjt8pR8XsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}