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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '747f3287590b806545a530ce7281a6060723c4a27e00d0883933a85a0e5458f4' 
  AND token = 'iUvyGDlHAJv+dT8iUR0/5x+3KPUb4Fj4yvKUg5rwNqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}