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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a7b46e7ce9d4b7f223b77f9b3c9d17372e2e2a84953bd200a7d39b5b6e004e' 
  AND token = 'zjNyIjmrAN4E5WZB835Yaa1XlhORNioGdZlfoZ/3YyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}