SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1563f083b67e68a5a43e043d7482377d0906f49c51e11a7719b569ed3048941c' 
  AND token = '7yUZQ+VdJeOC9oT27GYdYGT0ahJI4MpJe1wy7FyiWBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}