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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63b05d031999cc594dc8c7619056721197b6767807c7dddf5a28a5e869502236' 
  AND token = 'O3VDqTnRA3ZMUSIIE7MqK506SrrDPfnwvadj6wFvlRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}