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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efd5c2a44a96c74c49c6926e4afe2c23d3facbecad95efeca6c12357a493ffa' 
  AND token = 'lixqyJBYxhOTbbQxhNuY4AMNDJ4SS3WQDTSJKi1cFLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}