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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeffe5490c177b6e613ed47ad27361458b18ce497d4cd98326e51736d122abc9' 
  AND token = 'fcT0S4f0bqAnqzsWatL9UyHkMwYd8Flfn/dWXu76nj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}