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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '875f663d73a7019a3c80c060b328e1975b716b2685e76c44e5b63935857ab4ac' 
  AND token = 'wRsqxMZQe5W7EjMSF2ZxQkAlzbSI+Zt2nIZA/h/CWRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}