SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8744c85d870ceff1901cae53bb6ecd7ad33dd928bb27f8edf3fae1c6de267383' 
  AND token = 'JtkLVufQiZcNgphUCKIQQItEIEwQ2STuGNuK6niKREU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}