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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0654f9e2cd8abf47fb782d859bd5af70500db0b8aa2fa4ca6013f3437af36c4' 
  AND token = 'YOYdEO/3A3v2/O/JjmUFcwRdI0udIaayPQipotN5ne4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}