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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7a6c0bc440611df029a186ed4ce027d7f491cf39dfcbebef392370b855dcaa' 
  AND token = 'TG08f5cxbXzlkBp9voRwewwsaQ1f+sGuRqsLultuYZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}