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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58e608cf1557a08afae5a97f58543f0c01cdff0412d6a5d7a5af6581b71e74da' 
  AND token = '5qTPA9YxXqO4Ho2fQ00HI49pMwoyQM2wCDiR1pgUxV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}