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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b2417a21042991bd837789ac5f152a1e084284fb48bafec02a1734a0c286c04' 
  AND token = 'm+nAyvKN9l4njW/xF4br6aG8g4SYh16O4G0TZ0BYc0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}