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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0723aef9291760b1fdbb9648e4de5fb9c6a0a5ad403c4ae10582b270e72015b4' 
  AND token = '1OeL//ZbPi8UkU2FdtZmvY3XRwIElbDreXq9+XiAU3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}