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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e24d272bccc20a3a828a14f4b897e6d85e3b8a88e37732b8f7284d0d9fde77' 
  AND token = 'ECgoRZjKeNjEr0DD86Hk2VB4c/B+qvoJonVOpb2fMyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}