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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd13001afc0500db530e235eaf22545b3287297ded063af6cb8f76ff5549a220b' 
  AND token = 'VHS6nv02WKAqMCZECTYF7E3k4AcLPiVbhrPmNEho+9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}