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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '019cfe63ec11cc1268022bf7c9a51ca8acbc1110213e5d49a22cd1a336235ffb' 
  AND token = 'DGHLgx1N2qT7hohmp5DDo7v8Utx3PQHq7WlOkEM7dMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}