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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e6743dbae48103b9af9fea1634b0b188e8722b109acea2d3ad0cb9e339c1894' 
  AND token = 'N3KdAEGlsYhWafO1AW9raBTQ3lLefSgdUny1opgejEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}