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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ffe03a7968bf346188b2a5491577e2340af016e140223803359b9615e7c9639' 
  AND token = 'GwZ956EHd+S7SF5AfN5Xe0Z2hFR10fZCRTeYoetMXck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}